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Biological Activity
Glycyl-H 1152 2HCl is a selective and potent ROCK inhibitor (IC50 values are 0.0118, 2.35, 2.57, 3.26, > 10 and >10 uM for ROCKII, Aurora A, CAMKII, PKG, PKA and PKC respectively.)
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.25 mL | 111.26 mL | 222.52 mL |
| 0.5 mM | 4.45 mL | 22.25 mL | 44.5 mL |
| 1 mM | 2.23 mL | 11.13 mL | 22.25 mL |
| 5 mM | 0.45 mL | 2.23 mL | 4.45 mL |
*The above data is based on the productmolecular weight 449.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13659 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 913844-45-8 |
| Formula | C18H24N4O3S.2HCl |
| M. Wt | 449.4 |
| Purity | >98% |
| Synonyms | Rho Kinase Inhibitor IV |
| SMILES | C[[email protected]]1CN(CCCN1S(=O)(=O)C2=CC=CC3=C2C(=CN=C3)C)C(=O)CN.Cl.Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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