Glycyrrhetinic acid (Enoxolone)

Catalog No.: A10353

15-PGDH inhibitor

Glycyrrhetinic acid (Enoxolone)

Glycyrrhetinic acid (Enoxolone) Chemical Structure

CAS NO. 471-53-4

Glycyrrhetinic acid inhibits the enzymes (15-hydroxyprostaglandin dehydrogenase and delta-13-prostaglandin) that metabolize the prostaglandins PGE-2 and PGF-2α to their respective 15-keto-13,14-dihydro metabolites which are inactive.

Availability: In stock

Package Price Qty
500 mg

Regular Price: $50.00

Special Price $40.00

2000 mg

Regular Price: $160.00

Special Price $128.00

10mM * 1mL in DMSO

Regular Price: $59.00

Special Price $47.20

Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Glycyrrhetinic acid inhibits the enzymes (15-hydroxyprostaglandin dehydrogenase and delta-13-prostaglandin) that metabolize the prostaglandins PGE-2 and PGF-2α to their respective 15-keto-13,14-dihydro metabolites which are inactive.
Targets
15-hydroxyprostaglandin dehydrogenase
In vitro (25°C) DMSO 85 mg/mL (180.59 mM)
Water Insoluble
Ethanol Insoluble
In vivo 2% DMSO+corn oil 9 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.24 mL 106.22 mL 212.45 mL
0.5 mM 4.25 mL 21.24 mL 42.49 mL
1 mM 2.12 mL 10.62 mL 21.24 mL
5 mM 0.42 mL 2.12 mL 4.25 mL

*The above data is based on the productmolecular weight 470.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10353
Actions Inhibitor
CAS No. 471-53-4
Formula C30H46O4
M. Wt 470.7
Purity >98%
Synonyms Enoxolone, Glycyrrhetin, Uralenic acid, Glycyrrhetinate, Arthrodont
SMILES C[[email protected]]12CC[[email protected]](C[[email protected]]1C3=CC(=O)[[email protected]@H]4[[email protected]]5(CC[[email protected]@H](C([[email protected]@H]5CC[[email protected]]4([[email protected]@]3(CC2)C)C)(C)C)O)C)(C)C(=O)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy Glycyrrhetinic acid (Enoxolone) | Glycyrrhetinic acid (Enoxolone) Supplier | purchase | cost | manufacturer | order | distributor | buy 471-53-4| 471-53-4 Supplier | purchase 471-53-4 | 471-53-4 cost | 471-53-4 manufacturer | order 471-53-4 | 471-53-4 distributor
Rewards