Glycyrrhetinic acid (Enoxolone)

Catalog No.: A10353

15-PGDH inhibitor

Glycyrrhetinic acid (Enoxolone)

Glycyrrhetinic acid (Enoxolone) Chemical Structure

CAS NO. 471-53-4

Glycyrrhetinic acid inhibits the enzymes (15-hydroxyprostaglandin dehydrogenase and delta-13-prostaglandin) that metabolize the prostaglandins PGE-2 and PGF-2α to their respective 15-keto-13,14-dihydro metabolites which are inactive.

Availability: In stock

Package Price Qty
500 mg
$50.00
2000 mg
$160.00
10mM * 1mL in DMSO
$59.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Glycyrrhetinic acid inhibits the enzymes (15-hydroxyprostaglandin dehydrogenase and delta-13-prostaglandin) that metabolize the prostaglandins PGE-2 and PGF-2α to their respective 15-keto-13,14-dihydro metabolites which are inactive.
Targets
15-hydroxyprostaglandin dehydrogenase
In vitro DMSO 94 mg/mL (199.71 mM)
Water <1 mg/mL (<1 mM)
Ethanol 94 mg/mL (199.71 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.24 mL 106.22 mL 212.45 mL
0.5 mM 4.25 mL 21.24 mL 42.49 mL
1 mM 2.12 mL 10.62 mL 21.24 mL
5 mM 0.42 mL 2.12 mL 4.25 mL

*The above data is based on the productmolecular weight 470.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10353
Actions Inhibitor
M. Wt 470.7
Formula C30H46O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 471-53-4
Synonyms Enoxolone, Glycyrrhetin, Uralenic acid, Glycyrrhetinate, Arthrodont
SMILES C[[email protected]]12CC[[email protected]](C[[email protected]]1C3=CC(=O)[[email protected]@H]4[[email protected]]5(CC[[email protected]@H](C([[email protected]@H]5CC[[email protected]]4([[email protected]@]3(CC2)C)C)(C)C)O)C)(C)C(=O)O

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