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GM 6001


MMP inhibitor

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Catalog No. A13320

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
GM 6001 10mg A13320-10

Regular Price: €114.00

Special Price: €102.60

GM 6001 25mg A13320-25

Regular Price: €237.50

Special Price: €213.75

GM 6001 50mg A13320-50

Regular Price: €380.00

Special Price: €342.00

GM 6001 10mM * 1mL in DMSO A13320-10mM-D

Regular Price: €100.70

Special Price: €90.63

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

GM 6001 is a potent, reversible broad spectrum inhibitor of zinc-containing proteases, including matrix metalloproteinases (MMPs).

GM 6001

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Chemical Information

Catalog Num A13320
Actions Inhibitor
M. Wt 388.5
Formula C20H28N4O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 142880-36-2
Synonyms Galardin, Ilomastat
SMILES CC(C)C[[email protected]](CC(=O)NO)C(=O)N[[email protected]@H](CC1=CNC2=CC=CC=C21)C(=O)NC

Biological Activity

GM 6001 is a potent, reversible broad spectrum inhibitor of zinc-containing proteases, including matrix metalloproteinases (MMPs).
Target Value
MMP-8ki: 0.1nM
MMP-9ki: 0.2nM
MMP-26ki: 0.36nM
MMP-1ki: 0.4nM
MMP-2ki: 0.5nM
MMP-12ki: 3.6nM
MMP-7ki: 3.7nM
MMP-14ki: 13.4nM
MMP-3ki: 27nM


Solubility (25°C)* In vitro DMSO 78 mg/mL (200.79 mM)
Water <1 mg/mL (<1 mM)
Ethanol 8 mg/mL (20.59 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.74 mL 128.7 mL 257.4mL
0.5 mM 5.15 mL 25.74 mL 51.48 mL
1 mM 2.57 mL 12.87 mL 25.74 mL
5 mM 0.51 mL 2.57 mL 5.15 mL

*The above data is based on the productmolecular weight 388.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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