GM 6001

Catalog No.: A13320

MMP inhibitor

GM 6001

GM 6001 Chemical Structure

CAS NO. 142880-36-2

GM 6001 is a potent, reversible broad spectrum inhibitor of zinc-containing proteases, including matrix metalloproteinases (MMPs).

Availability: In stock

Package Price Qty
10 mg
$120.00
25 mg
$250.00
50 mg
$400.00
10mM * 1mL in DMSO
$106.00
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Biological Activity

GM 6001 is a potent, reversible broad spectrum inhibitor of zinc-containing proteases, including matrix metalloproteinases (MMPs).
Targets
Target Value
MMP-8ki: 0.1nM
MMP-9ki: 0.2nM
MMP-26ki: 0.36nM
MMP-1ki: 0.4nM
MMP-2ki: 0.5nM
MMP-12ki: 3.6nM
MMP-7ki: 3.7nM
MMP-14ki: 13.4nM
MMP-3ki: 27nM
In vitro (25°C) DMSO 73 mg/mL (187.92 mM)
Water Insoluble
Ethanol Warmed: 7 mg/mL (18.02 mM)
In vivo 2% DMSO+40% PEG 300+2% Tween 80+ddH2O 10 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.74 mL 128.7 mL 257.4 mL
0.5 mM 5.15 mL 25.74 mL 51.48 mL
1 mM 2.57 mL 12.87 mL 25.74 mL
5 mM 0.51 mL 2.57 mL 5.15 mL

*The above data is based on the productmolecular weight 388.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13320
Actions Inhibitor
CAS No. 142880-36-2
Formula C20H28N4O4
M. Wt 388.5
Purity >98%
Synonyms Galardin, Ilomastat, GM-6001
SMILES CC(C)C[[email protected]](CC(=O)NO)C(=O)N[[email protected]@H](CC1=CNC2=CC=CC=C21)C(=O)NC
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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