Total item
Cart Subtotal
$0.00 Biological Activity
GM 6001 is a potent, reversible broad spectrum inhibitor of zinc-containing proteases, including matrix metalloproteinases (MMPs).
Targets
| Target | Value |
|---|---|
| MMP-8 | ki: 0.1nM |
| MMP-9 | ki: 0.2nM |
| MMP-26 | ki: 0.36nM |
| MMP-1 | ki: 0.4nM |
| MMP-2 | ki: 0.5nM |
| MMP-12 | ki: 3.6nM |
| MMP-7 | ki: 3.7nM |
| MMP-14 | ki: 13.4nM |
| MMP-3 | ki: 27nM |
| In vitro (25°C) | DMSO | 73 mg/mL (187.92 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 7 mg/mL (18.02 mM) | ||
| In vivo | 2% DMSO+40% PEG 300+2% Tween 80+ddH2O | 10 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.74 mL | 128.7 mL | 257.4 mL |
| 0.5 mM | 5.15 mL | 25.74 mL | 51.48 mL |
| 1 mM | 2.57 mL | 12.87 mL | 25.74 mL |
| 5 mM | 0.51 mL | 2.57 mL | 5.15 mL |
*The above data is based on the productmolecular weight 388.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13320 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 142880-36-2 |
| Formula | C20H28N4O4 |
| M. Wt | 388.5 |
| Purity | >98% |
| Synonyms | Galardin, Ilomastat, GM-6001 |
| SMILES | CC(C)C[[email protected]](CC(=O)NO)C(=O)N[[email protected]@H](CC1=CNC2=CC=CC=C21)C(=O)NC |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Product Tags
Product Questions
Product Questions
No Questions
Keywords:buy GM 6001 | GM 6001 Supplier | purchase | cost | manufacturer | order | distributor | buy 142880-36-2| 142880-36-2 Supplier | purchase 142880-36-2 | 142880-36-2 cost | 142880-36-2 manufacturer | order 142880-36-2 | 142880-36-2 distributor
Adooq Quality Guarantee
We promise all products perform as described.