GNE-317

Catalog No.: A13992

PI3K inhibitor

GNE-317

GNE-317 Chemical Structure

CAS NO. 1394076-92-6

GNE-317 is a potent PI3K inhibitor that can cross the Blood brain barrier; shows potent suppression of the PI3K pathway in the brain of mice with intact BBB.

Availability: In stock

Package Price Qty
5 mg
$90.00
10 mg
$140.00
50 mg
$420.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

GNE-317 is a potent PI3K inhibitor that can cross the Blood brain barrier; shows potent suppression of the PI3K pathway in the brain of mice with intact BBB.
Targets
PI3K
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.13 mL 120.63 mL 241.27 mL
0.5 mM 4.83 mL 24.13 mL 48.25 mL
1 mM 2.41 mL 12.06 mL 24.13 mL
5 mM 0.48 mL 2.41 mL 4.83 mL

*The above data is based on the productmolecular weight 414.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A13992
Actions Inhibitor
M. Wt 414.48
Formula C19H22N6O3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1394076-92-6
Synonyms GNE317, GNE 317
SMILES COC1(COC1)C2=C(C)C3=C(S2)C(N4CCOCC4)=NC(C5=CN=C(N)N=C5)=N3

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