GPR139 agonist-2 is a selective agonist targeting the GPR139 receptor, demonstrating a potent EC50 of 24.7 nM. This compound has shown promising biological activity by rescuing social interaction deficits and ameliorating cognitive impairments in murine models of schizophrenia. GPR139 agonist-2 holds potential for use in antipsychotic drug research and the exploration of novel therapeutic strategies for schizophrenia.
GPR139 agonist-2 is a selective agonist targeting the GPR139 receptor, demonstrating a potent EC50 of 24.7 nM. This compound has shown promising biological activity by rescuing social interaction deficits and ameliorating cognitive impairments in murine models of schizophrenia. GPR139 agonist-2 holds potential for use in antipsychotic drug research and the exploration of novel therapeutic strategies for schizophrenia.
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