Biological Activity
GRL0617 is a potent, selective and competitive noncovalent inhibitor of SARS PLPro, with an IC50 of 0.6 μM, and with a Ki of 0.49 μM.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 32.85 mL | 164.26 mL | 328.53 mL |
0.5 mM | 6.57 mL | 32.85 mL | 65.71 mL |
1 mM | 3.29 mL | 16.43 mL | 32.85 mL |
5 mM | 0.66 mL | 3.29 mL | 6.57 mL |
*The above data is based on the productmolecular weight 304.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A18780 |
---|---|
Actions | Inhibitor |
M. Wt | 304.39 |
Formula | C20H20N2O |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 1093070-16-6 |
Synonyms | GRL 0617, GRL-0617 |
SMILES | O=C(N[[email protected]@H](C1=C2C=CC=CC2=CC=C1)C)C3=CC(N)=CC=C3C |
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