GS-9256

Catalog No.: A13526

HCV NS3 inhibitor

GS-9256

GS-9256 Chemical Structure

CAS NO. 1001094-46-7

GS-9451 is a potent macrocyclic HCV NS3 PI that achieved a median maximal change in HCV RNA of 3.6 log10 IU/mL (range, -4.7 log10 to -3.1 log10 IU/mL) following 3-day monotherapy in treatment-nave patients with HCV genotype 1 infection during phase I.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $180.00

Special Price $144.00

25 mg

Regular Price: $400.00

Special Price $320.00

50 mg

Regular Price: $700.00

Special Price $560.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

GS-9451 is a potent macrocyclic HCV NS3 PI that achieved a median maximal change in HCV RNA of 3.6 log10 IU/mL (range, -4.7 log10 to -3.1 log10 IU/mL) following 3-day monotherapy in treatment-nave patients with HCV genotype 1 infection during phase I.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 10.44 mL 52.22 mL 104.44 mL
0.5 mM 2.09 mL 10.44 mL 20.89 mL
1 mM 1.04 mL 5.22 mL 10.44 mL
5 mM 0.21 mL 1.04 mL 2.09 mL

*The above data is based on the productmolecular weight 957.461. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A13526
Actions Inhibitor
M. Wt 957.461
Formula C46H56ClF2N6O8PS
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1001094-46-7
Synonyms GS 9256, GS9256
SMILES CC(C)NC1=NC(=CS1)C2=NC3=C(C=CC(=C3Cl)OC)C(=C2)O[[email protected]@H]4C[[email protected]]5C(=O)N[[email protected]@]6(C[[email protected]]6CCCCCCC[[email protected]@H](C(=O)N5C4)NC(=O)OC7CCCC7)P(=O)(CC8=C(C=CC=C8F)F)O

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