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HCV NS3/4A protease inhibitor

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Catalog No. A14046

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
GS-9451 2mg A14046-2
GS-9451 5mg A14046-5

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

GS-9451, a novel hepatitis C virus (HCV) nonstructural 3/4a (NS3/4a) protease inhibitor, is highly active in patients infected with HCV genotype 1 (GT 1).


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Chemical Information

Catalog Num A14046
Actions Inhibitor
M. Wt 910.52
Formula C45H60ClN7O9S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1310824-24-8
Synonyms GS 9451, GS9451
SMILES CC[[email protected]@H]1C[[email protected]@]1(C(=O)O)NC(=O)[[email protected]@H]2C[[email protected]](CN2C(=O)[[email protected]](C(C)(C)C)NC(=O)OC3C[[email protected]]4C[[email protected]]4C3)OC5=CC(=NC6=C5C=CC(=C6Cl)OCCN7CCOCC7)C8=CSC(=N8)NC(C)C

Biological Activity

GS-9451, a novel hepatitis C virus (HCV) nonstructural 3/4a (NS3/4a) protease inhibitor, is highly active in patients infected with HCV genotype 1 (GT 1).

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 10.98 mL 54.91 mL 109.83mL
0.5 mM 2.2 mL 10.98 mL 21.97 mL
1 mM 1.1 mL 5.49 mL 10.98 mL
5 mM 0.22 mL 1.1 mL 2.2 mL

*The above data is based on the productmolecular weight 910.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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