GS-9451

Catalog No.: A14046

HCV NS3/4A protease inhibitor

GS-9451

GS-9451 Chemical Structure

CAS NO. 1310824-24-8

GS-9451, a novel hepatitis C virus (HCV) nonstructural 3/4a (NS3/4a) protease inhibitor, is highly active in patients infected with HCV genotype 1 (GT 1).

Availability: In stock

Package Price Qty
2 mg

Regular Price: $350.00

Special Price $280.00

5 mg

Regular Price: $600.00

Special Price $480.00

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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

GS-9451, a novel hepatitis C virus (HCV) nonstructural 3/4a (NS3/4a) protease inhibitor, is highly active in patients infected with HCV genotype 1 (GT 1).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 10.98 mL 54.91 mL 109.83 mL
0.5 mM 2.2 mL 10.98 mL 21.97 mL
1 mM 1.1 mL 5.49 mL 10.98 mL
5 mM 0.22 mL 1.1 mL 2.2 mL

*The above data is based on the productmolecular weight 910.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14046
Actions Inhibitor
CAS No. 1310824-24-8
Formula C45H60ClN7O9S
M. Wt 910.52
Purity >98%
Synonyms GS 9451, GS9451
SMILES CC[[email protected]@H]1C[[email protected]@]1(C(=O)O)NC(=O)[[email protected]@H]2C[[email protected]](CN2C(=O)[[email protected]](C(C)(C)C)NC(=O)OC3C[[email protected]]4C[[email protected]]4C3)OC5=CC(=NC6=C5C=CC(=C6Cl)OCCN7CCOCC7)C8=CSC(=N8)NC(C)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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