GS-9667 is a selective partial agonist of the A1 adenosine receptor (A1AdoR). This N6-5'-substituted adenosine analog effectively reduces cyclic AMP levels and inhibits the release of nonesterified fatty acids from epididymal adipocytes, demonstrating IC50 values of 6 nM and 44 nM, respectively. Its ability to inhibit lipolysis suggests potential applications in research related to Type 2 diabetes (T2DM) and dyslipidemia by lowering free fatty acids (FFA).
GS-9667 is a selective partial agonist of the A1 adenosine receptor (A1AdoR). This N6-5'-substituted adenosine analog effectively reduces cyclic AMP levels and inhibits the release of nonesterified fatty acids from epididymal adipocytes, demonstrating IC50 values of 6 nM and 44 nM, respectively. Its ability to inhibit lipolysis suggests potential applications in research related to Type 2 diabetes (T2DM) and dyslipidemia by lowering free fatty acids (FFA).
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
