GSK-5498A

Catalog No.: A21862

CARC blocker

GSK-5498A

GSK-5498A Chemical Structure

CAS NO. 1253186-49-0

GSK-5498A is a selective small molecule blocker of CARC (IC50, 1 μM); inhibits mediator release from mast cells, and pro-inflammatory cytokine release from T-cells in a variety of species.

Availability: In stock

Package Price Qty
5 mg
$378.00
10 mg
$651.00
50 mg
$1,932.00
100 mg
$3,864.00
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Biological Activity

GSK-5498A is a selective small molecule blocker of CARC (IC50, 1 μM); inhibits mediator release from mast cells, and pro-inflammatory cytokine release from T-cells in a variety of species.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.04 mL 125.22 mL 250.44 mL
0.5 mM 5.01 mL 25.04 mL 50.09 mL
1 mM 2.5 mL 12.52 mL 25.04 mL
5 mM 0.5 mL 2.5 mL 5.01 mL

*The above data is based on the productmolecular weight 399.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21862
Actions Blocker
CAS No. 1253186-49-0
Formula C18H11F6N3O
M. Wt 399.29
Purity >98%
Synonyms GSK 5498A, GSK5498A
SMILES O=C(NC1=NN(CC2=C(F)C=CC=C2C(F)(F)F)C=C1)C3=C(F)C=CC=C3F
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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