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Biological Activity
GSK-5498A is a selective small molecule blocker of CARC (IC50, 1 μM); inhibits mediator release from mast cells, and pro-inflammatory cytokine release from T-cells in a variety of species.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.04 mL | 125.22 mL | 250.44 mL |
| 0.5 mM | 5.01 mL | 25.04 mL | 50.09 mL |
| 1 mM | 2.5 mL | 12.52 mL | 25.04 mL |
| 5 mM | 0.5 mL | 2.5 mL | 5.01 mL |
*The above data is based on the productmolecular weight 399.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21862 |
|---|---|
| Actions | Blocker |
| CAS No. | 1253186-49-0 |
| Formula | C18H11F6N3O |
| M. Wt | 399.29 |
| Purity | >98% |
| Synonyms | GSK 5498A, GSK5498A |
| SMILES | O=C(NC1=NN(CC2=C(F)C=CC=C2C(F)(F)F)C=C1)C3=C(F)C=CC=C3F |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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