GSK-J1 sodium

Name: GSK-J1 sodium
Brand: Adooq Bioscience
SKU: A29243
Rating: 5 (288 reviews)

Catalog No.: A29243

JMJD3/KDM6B Inhibitor

GSK-J1 sodium is a selective inhibitor of the histone demethylases JMJD3 (KDM6B) and UTX (KDM6A), exhibiting an IC50 value of 60 nM for KDM6B. This compound modulates H3K27me3/me2 levels, thereby influencing gene expression and cellular differentiation. GSK-J1 sodium is useful in research applications focused on epigenetic regulation, cancer biology, and developmental processes.

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GSK-J1 sodium 1797832-71-3 JMJD3/KDM6B Inhibitor

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Grouped product items
Size	Price	Stock
1mg	$90.00	In stock
5mg	$345.00	In stock
10mg	$515.00	In stock
50mg	$2,240.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	GSK-J1 sodium is a selective inhibitor of the histone demethylases JMJD3 (KDM6B) and UTX (KDM6A), exhibiting an IC50 value of 60 nM for KDM6B. This compound modulates H3K27me3/me2 levels, thereby influencing gene expression and cellular differentiation. GSK-J1 sodium is useful in research applications focused on epigenetic regulation, cancer biology, and developmental processes.

Product Information

Catalog Num	A29243
Formula	C22H22N5NaO2
Molecular Weight	411.43
CAS Number	1797832-71-3
SMILES	O=C(CCNC1=CC(N2CCC3=C(CC2)C=CC=C3)=NC(C4=CC=CC=N4)=N1)O[Na]

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