GSK2018682 hydrochloride is a specific agonist for the sphingosine-1-phosphate receptors S1P1 and S1P5, exhibiting pEC50 values of 7.7 and 7.2, respectively. It shows no agonist activity toward the S1P2, S1P3, or S1P4 receptors. This compound is primarily utilized in research investigating multiple sclerosis and related neurological disorders, offering insights into the modulation of immune responses and vascular integrity.
GSK2018682 hydrochloride is a specific agonist for the sphingosine-1-phosphate receptors S1P1 and S1P5, exhibiting pEC50 values of 7.7 and 7.2, respectively. It shows no agonist activity toward the S1P2, S1P3, or S1P4 receptors. This compound is primarily utilized in research investigating multiple sclerosis and related neurological disorders, offering insights into the modulation of immune responses and vascular integrity.
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