United States
You have no items in your shopping cart.
Publications citing Adooq Products
GSK2656157 Citations (1)
- Kosuke Ishikawa, .et al. A highly sensitive trap vector system for isolating reporter cells and identification of responsive genes, Biology Methods and Protocols, 2018, 1–10
Chemical Information
| Catalog Num | A13577 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 416.45 |
| Formula | C23H21FN6O |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1337532-29-2 |
| Synonyms | GSK 2656157 |
| SMILES code | CC1=NC(=CC=C1)CC(=O)N2CCC3=C2C=CC(=C3F)C4=CN(C5=C4C(=NC=N5)N)C |
| Chemical Name | 1-(5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoroindolin-1-yl)-2-(6-methylpyridin-2-yl)ethanone |
Description |
GSK2656157 is an ATP-competitive inhibitor of PERK enzyme activity with an IC(50) of 0.9 nmol/L. It is highly selective for PERK with IC(50) values >100 nmol/L against a panel of 300 kinases. | ||||||||||
Targets |
|
||||||||||
| Solubility (25°C)* | In vitro | DMSO | 32 mg/mL (76.83 mM) |
|---|---|---|---|
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | <1 mg/mL (<1 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.01 mL | 120.06 mL | 240.12mL |
| 0.5 mM | 4.8 mL | 24.01 mL | 48.02 mL |
| 1 mM | 2.4 mL | 12.01 mL | 24.01 mL |
| 5 mM | 0.48 mL | 2.4 mL | 4.8 mL |
*The above data is based on the productmolecular weight 416.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Ordering online
To place an order online, simply browse to the product you are interested in and click on the 'Add to Cart' button. To complete this process, you will need to confirm the size and quantity of the products that you require.
To complete an order you will need to register using our simple online registration process. We do not share your contact details with any third parties.
When you are ready to check out simply enter your PO number to complete the ordering process. Please ensure that you send us a copy of your PO by fax or email afterwards. We will then liaise with you or your purchasing department to confirm the order.
Found your products but not ready to order?
Why not use our WishList feature to store lists of products? This convenient feature allows you to manage lists, append notes to products and share lists with co-workers or colleagues.
Ordering offline
You can email or fax us your purchase order and we will place the order for you. You can also phone us to place the order. Our contact details are:
- Tel: 866-930-6790
- Fax: 323-606-8156
- Email: [email protected]
We require the following information to process your order:
- The catalog number for each product.
- Your email address or fax number.
- Your name and telephone number.
- Shipping address and billing address.
- Purchase order numbers.
Similar product(s)
Special Price Starting at:
$76.50
GSK2606414 is an orally available, potent, and selective PERK inhibitor with IC50 of 0.4 nM. ...
Special Price Starting at: $76.50
Special Price Starting at:
$40.00
KJ Pyr 9 is a novel small-molecule inhibitor of MYC, KJ-Pyr-9, from a Krhnke pyridine library. ...
Special Price Starting at: $40.00
Special Price Starting at:
$81.00
ISRIB (trans-isomer) is a potent and selective small molecule inhibitor of PERK signaling (IC50 ~5 nM) that can potently reverse the effects of eIF2α phosphorylation.
...
Special Price Starting at: $81.00
Special Price Starting at:
$49.50
10058-F4 is a c-Myc inhibitor that prevents c-Myc/Max dimerization. ...
Special Price Starting at: $49.50
Keywords:buy GSK2656157 | GSK2656157 Supplier | purchase GSK2656157 | GSK2656157 cost | GSK2656157 manufacturer | order GSK2656157 | GSK2656157 distributor | buy 1337532-29-2| 1337532-29-2 Supplier | purchase 1337532-29-2 | 1337532-29-2 cost | 1337532-29-2 manufacturer | order 1337532-29-2 | 1337532-29-2 distributor
We Using Safe Payments:
