GSK3532795 oxalate is a potent second-generation inhibitor of HIV-1 maturation, acting primarily through the disruption of viral particle assembly. It exhibits notable efficacy with EC50 values of 1.9 nM for HIV-1 wild type, 10.2 nM in human serum, as well as 2.7 nM and 13 nM for the HIV-1 V370A and ΔV370 variants, respectively. This compound is essential for research focused on HIV-1 infection mechanisms and therapeutic strategies.
GSK3532795 oxalate is a potent second-generation inhibitor of HIV-1 maturation, acting primarily through the disruption of viral particle assembly. It exhibits notable efficacy with EC50 values of 1.9 nM for HIV-1 wild type, 10.2 nM in human serum, as well as 2.7 nM and 13 nM for the HIV-1 V370A and ΔV370 variants, respectively. This compound is essential for research focused on HIV-1 infection mechanisms and therapeutic strategies.
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