GSK356278 is a selective phosphodiesterase 4 (PDE4) inhibitor that demonstrates potent activity with pIC50 values of 8.6, 8.8, and 8.7 against human PDE4A, PDE4B, and PDE4D, respectively. This orally bioavailable compound is characterized by its ability to penetrate the blood-brain barrier, exhibiting anti-inflammatory effects alongside anxiolytic and cognition-enhancing properties. GSK356278 is valuable for research in neurodegenerative diseases and mood disorders, making it a significant tool for understanding PDE4 modulation in therapeutic contexts.
GSK356278 is a selective phosphodiesterase 4 (PDE4) inhibitor that demonstrates potent activity with pIC50 values of 8.6, 8.8, and 8.7 against human PDE4A, PDE4B, and PDE4D, respectively. This orally bioavailable compound is characterized by its ability to penetrate the blood-brain barrier, exhibiting anti-inflammatory effects alongside anxiolytic and cognition-enhancing properties. GSK356278 is valuable for research in neurodegenerative diseases and mood disorders, making it a significant tool for understanding PDE4 modulation in therapeutic contexts.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
