Catalog No.: A15896
AMPK activator
GSK621 is a potent and selective AMPK agonist.
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Product Name Stock
GSK621 5mg
GSK621 10mg
GSK621 25mg
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's GSK621 has been cited by 1 publications
  • Harvey W. Smith, .et al. , Nat Commun, 2019, 10, 2901(2019) PMID: 31263101
  • Biological Activity
    Discription GSK621 is a potent and selective AMPK agonist.
    Target Value
    Product Information
    Catalog Num A15896
    Formula C26H20ClN3O5
    Molecular Weight 489.91
    CAS Number 1346607-05-3
    SMILES O=C1NC2=C(N(C3=CC=C(C4=CC=CC(OC)=C4O)C=C3)C(Cl)=C2)C(N1C5=CC=CC(OC)=C5)=O
    Synonyms GSK-621, GSK 621

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    In vitro (25°C) DMSO 84 mg/mL (171.46 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 2% DMSO+30% PEG 300+5% Tween 80+ddH2O 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 20.41 mL 102.06 mL 204.12 mL
    0.5 mM 4.08 mL 20.41 mL 40.82 mL
    1 mM 2.04 mL 10.21 mL 20.41 mL
    5 mM 0.41 mL 2.04 mL 4.08 mL
    Useful Calculator

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    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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