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- Harvey W. Smith, .et al. An ErbB2/c-Src axis links bioenergetics with PRC2 translation to drive epigenetic reprogramming and mammary tumorigenesis, Nat Commun, 2019, 10, 2901(2019) PMID: 31263101
Biological Activity
GSK621 is a potent and selective AMPK agonist.
Targets
| AMPK | ||||
| In vitro (25°C) | DMSO | 84 mg/mL (171.46 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 2% DMSO+30% PEG 300+5% Tween 80+ddH2O | 4 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.41 mL | 102.06 mL | 204.12 mL |
| 0.5 mM | 4.08 mL | 20.41 mL | 40.82 mL |
| 1 mM | 2.04 mL | 10.21 mL | 20.41 mL |
| 5 mM | 0.41 mL | 2.04 mL | 4.08 mL |
*The above data is based on the productmolecular weight 489.91. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A15896 |
|---|---|
| Actions | Activator |
| CAS No. | 1346607-05-3 |
| Formula | C26H20ClN3O5 |
| M. Wt | 489.91 |
| Purity | >98% |
| Synonyms | GSK-621, GSK 621 |
| SMILES | O=C1NC2=C(N(C3=CC=C(C4=CC=CC(OC)=C4O)C=C3)C(Cl)=C2)C(N1C5=CC=CC(OC)=C5)=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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Contact information
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