Trusted by 10,000+ Scientists since 2006



AKT inhibitor

0 Customer Reviews
Catalog No. A11030

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
GSK690693 10mg A11030-10

Regular Price: $120.00

Special Price: $108.00

GSK690693 25mg A11030-25

Regular Price: $220.00

Special Price: $198.00

GSK690693 50mg A11030-50

Regular Price: $360.00

Special Price: $324.00

GSK690693 100mg A11030-100

Regular Price: $600.00

Special Price: $540.00

GSK690693 10mM * 1mL in DMSO A11030-10mM-D

Regular Price: $75.00

Special Price: $67.50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

GSK690693 is a novel ATP-competitive, low-nanomolar pan-Akt kinase inhibitor (IC50 values are 2, 13 and 9 nM of Akt1, 2 and 3 respectively).


Double click on above image to view full picture

Zoom Out
Zoom In

More Views

Publications citing Adooq Products
GSK690693 Citations (1)
  • Khan MI, .et al. Thalidomide attenuates development of morphine dependence in mice by inhibiting PI3K/Akt and nitric oxide signaling pathways, Prog Neuropsychopharmacol Biol Psychiatry, 2018, Mar 2;82:39-48 PMID: 9223784

Chemical Information

Catalog Num A11030
Actions Inhibitor
M. Wt 425.5
Formula C21H27N7O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 937174-76-0
Synonyms GSK-690693
SMILES CCN1C2=C(C(=NC=C2OC[[email protected]]3CCCNC3)C#CC(C)(C)O)N=C1C4=NON=C4N

Biological Activity

GSK690693 is a novel ATP-competitive, low-nanomolar pan-Akt kinase inhibitor (IC50 values are 2, 13 and 9 nM of Akt1, 2 and 3 respectively).
Target Value
Akt1IC50: 2nM
PKCηIC50: 2nM
PKCθIC50: 2nM
PrkXIC50: 5nM
Akt3IC50: 9nM
Akt2IC50: 13nM
PKCδIC50: 14nM
PKCβIC50: 19nM
PKCεIC50: 21nM
PKAIC50: 24nM
PKG1βIC50: 33nM


Solubility (25°C) * In vitro DMSO 39 mg/mL (91.66 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 15% Captisol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.5 mL 117.51 mL 235.02mL
0.5 mM 4.7 mL 23.5 mL 47 mL
1 mM 2.35 mL 11.75 mL 23.5 mL
5 mM 0.47 mL 2.35 mL 4.7 mL

*The above data is based on the productmolecular weight 425.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Ordering online

To place an order online, simply browse to the product you are interested in and click on the 'Add to Cart' button. To complete this process, you will need to confirm the size and quantity of the products that you require.

To complete an order you will need to register using our simple online registration process. We do not share your contact details with any third parties.

When you are ready to check out simply enter your PO number to complete the ordering process. Please ensure that you send us a copy of your PO by fax or email afterwards.  We will then liaise with you or your purchasing department to confirm the order.

Found your products but not ready to order?

Why not use our WishList feature to store lists of products? This convenient feature allows you to manage lists, append notes to products and share lists with co-workers or colleagues.

Ordering offline

You can email or fax us your purchase order and we will place the order for you. You can also phone us to place the order.  Our contact details are:

We require the following information to process your order:
  • The catalog number for each product. 
  • Your email address or fax number. 
  • Your name and telephone number. 
  • Shipping address and billing address.
  • Purchase order numbers.

Product Tags

Use spaces to separate tags. Use single quotes (') for phrases.

Similar product(s)

Keywords:buy GSK690693 | GSK690693 Supplier | purchase GSK690693 | GSK690693 cost | GSK690693 manufacturer | order GSK690693 | GSK690693 distributor | buy 937174-76-0| 937174-76-0 Supplier | purchase 937174-76-0 | 937174-76-0 cost | 937174-76-0 manufacturer | order 937174-76-0 | 937174-76-0 distributor