GSK690693

Catalog No.: A11030

AKT inhibitor

GSK690693

GSK690693 Chemical Structure

CAS NO. 937174-76-0

GSK690693 is a novel ATP-competitive, low-nanomolar pan-Akt kinase inhibitor (IC50 values are 2, 13 and 9 nM of Akt1, 2 and 3 respectively).

Availability: In stock

Package Price Qty
10 mg

Regular Price: $120.00

Special Price $108.00

25 mg

Regular Price: $220.00

Special Price $198.00

50 mg

Regular Price: $360.00

Special Price $324.00

100 mg

Regular Price: $600.00

Special Price $540.00

10mM * 1mL in DMSO

Regular Price: $75.00

Special Price $67.50

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

GSK690693 is a novel ATP-competitive, low-nanomolar pan-Akt kinase inhibitor (IC50 values are 2, 13 and 9 nM of Akt1, 2 and 3 respectively).
Targets
Target Value
Akt1IC50: 2nM
PKCηIC50: 2nM
PKCθIC50: 2nM
PrkXIC50: 5nM
Akt3IC50: 9nM
Akt2IC50: 13nM
PKCδIC50: 14nM
PKCβIC50: 19nM
PKCεIC50: 21nM
PKAIC50: 24nM
PKG1βIC50: 33nM
In vitro (25°C) DMSO 39 mg/mL (91.66 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 15% Captisol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.5 mL 117.51 mL 235.02 mL
0.5 mM 4.7 mL 23.5 mL 47 mL
1 mM 2.35 mL 11.75 mL 23.5 mL
5 mM 0.47 mL 2.35 mL 4.7 mL

*The above data is based on the productmolecular weight 425.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11030
Actions Inhibitor
M. Wt 425.5
Formula C21H27N7O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 937174-76-0
Synonyms GSK-690693
SMILES CCN1C2=C(C(=NC=C2OC[[email protected]]3CCCNC3)C#CC(C)(C)O)N=C1C4=NON=C4N

Product Tags

Product Tags

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
You may also be interested in the following product(s)
Keywords:buy GSK690693 | GSK690693 Supplier | purchase GSK690693 | GSK690693 cost | GSK690693 manufacturer | order GSK690693 | GSK690693 distributor | buy 937174-76-0| 937174-76-0 Supplier | purchase 937174-76-0 | 937174-76-0 cost | 937174-76-0 manufacturer | order 937174-76-0 | 937174-76-0 distributor
Rewards