Biological Activity
GSK8612 is a highly selective and potent Tank-binding Kinase-1 (TBK1) inhibitor, with a pIC50 of 6.8 for recombinant TBK1.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 19.22 mL | 96.09 mL | 192.19 mL |
0.5 mM | 3.84 mL | 19.22 mL | 38.44 mL |
1 mM | 1.92 mL | 9.61 mL | 19.22 mL |
5 mM | 0.38 mL | 1.92 mL | 3.84 mL |
*The above data is based on the productmolecular weight 520.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A19438 |
---|---|
Actions | Inhibitor |
M. Wt | 520.33 |
Formula | C17H17BrF3N7O2S |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 2361659-62-1 |
Synonyms | GSK-8612; GSK 8612 |
SMILES | NS(C1=CC=C(CNC2=C(Br)C=NC(NC3=CN(CC(F)(F)F)N=C3C)=N2)C=C1)(=O)=O |
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