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GW 4869


N-SMase inhibitor

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Catalog No. A11974

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
GW 4869 5mg A11974-5

Regular Price: $100.00

Special Price: $90.00

GW 4869 10mg A11974-10

Regular Price: $180.00

Special Price: $162.00

GW 4869 50mg A11974-50

Regular Price: $750.00

Special Price: $675.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

W4869 is a cell permeable, selective inhibitor of N-SMase (neutral sphingomyelinase).

GW 4869

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Chemical Information

Catalog Num A11974
Actions Inhibitor
M. Wt 577.5
Formula C30H28N6O2 · 2HCl
Solubility DMSO
Purity >90%
Storage at -20°C 3 years Powder
CAS No. 6823-69-4
Synonyms GW-4869, GW4869
SMILES C1NC(=NC1)C2=CC=C(C=C2)NC(=O)/C=C/C3=CC=C(C=C3)/C=C/C(=O)NC4=CC=C(C=C4)C5=NCCN5.O.Cl.Cl

Biological Activity

W4869 is a cell permeable, selective inhibitor of N-SMase (neutral sphingomyelinase).

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.32 mL 86.58 mL 173.16mL
0.5 mM 3.46 mL 17.32 mL 34.63 mL
1 mM 1.73 mL 8.66 mL 17.32 mL
5 mM 0.35 mL 1.73 mL 3.46 mL

*The above data is based on the productmolecular weight 577.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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