GW 833972A is a selective agonist of the CB2 receptor, exhibiting a pEC50 value of 7.3 for human CB2. With approximately 1000-fold higher selectivity for the CB2 receptor over CB1, GW 833972A effectively inhibits induced neuronal depolarization and alleviates cough reflex in guinea pig models. This compound is valuable for research into chronic cough mechanisms and potential therapeutic interventions.
GW 833972A is a selective agonist of the CB2 receptor, exhibiting a pEC50 value of 7.3 for human CB2. With approximately 1000-fold higher selectivity for the CB2 receptor over CB1, GW 833972A effectively inhibits induced neuronal depolarization and alleviates cough reflex in guinea pig models. This compound is valuable for research into chronic cough mechanisms and potential therapeutic interventions.
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