GW1929 hydrochloride is a potent agonist of the peroxisome proliferator-activated receptor-γ (PPARγ), exhibiting a pKi of 8.84 for human PPAR-γ and pEC50 values of 8.56 for human PPAR-γ and 8.27 for murine PPAR-γ. This compound demonstrates significant antidiabetic activity and potential neuroprotective effects by suppressing neuronal apoptosis and exhibiting anti-inflammatory properties. It is a valuable tool for investigating metabolic disorders, neurodegenerative diseases, and the mechanisms of inflammation in research applications.
GW1929 hydrochloride is a potent agonist of the peroxisome proliferator-activated receptor-γ (PPARγ), exhibiting a pKi of 8.84 for human PPAR-γ and pEC50 values of 8.56 for human PPAR-γ and 8.27 for murine PPAR-γ. This compound demonstrates significant antidiabetic activity and potential neuroprotective effects by suppressing neuronal apoptosis and exhibiting anti-inflammatory properties. It is a valuable tool for investigating metabolic disorders, neurodegenerative diseases, and the mechanisms of inflammation in research applications.
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