GW9508

Catalog No.: A11965
GPR40 Inhibitor
GW 9508 is a cell-permeable aminophenylpropanoate that acts as a potent and selective agonist for the G-protein coupled receptor (GPCR) GRP40/FFA1 receptor (EC50 ?50 nM) with reduced activity towards family members GRP120 (EC50 ?3.5 μM), GRP41/GRP43 (EC50 >50 μM), as well as a panel of eight other free fatty acid (FFA) and prostaglandin receptors.
Grouped product items
Size Price Stock Qty
5mg
$20.00
In stock
10mg
$25.00
In stock
25mg
$40.00
In stock
50mg
$70.00
In stock
100mg
$135.00
In stock
200mg
$205.00
In stock
10mM * 1mL in DMSO
$20.00
In stock
Bulk Size
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Biological Activity
Discription GW 9508 is a cell-permeable aminophenylpropanoate that acts as a potent and selective agonist for the G-protein coupled receptor (GPCR) GRP40/FFA1 receptor (EC50 ?50 nM) with reduced activity towards family members GRP120 (EC50 ?3.5 μM), GRP41/GRP43 (EC50 >50 μM), as well as a panel of eight other free fatty acid (FFA) and prostaglandin receptors.
Targets
Target Value
Cell Research
Cell Line Type Value Description References
Product Information
Catalog Num A11965
Formula C22H21NO3
Molecular Weight 347.4
CAS Number 885101-89-3
SMILES C1=CC=C(C=C1)OC2=CC=CC(=C2)CNC3=CC=C(C=C3)CCC(=O)O
Synonyms GW 9508, GW-9508
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 63 mg/mL (181.34 mM)
Water Insoluble
Ethanol 63 mg/mL (181.34 mM)
In vivo 2% DMSO+40% PEG 300+2% Tween 80+ddH2O 1 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.79 mL 143.93 mL 287.85 mL
0.5 mM 5.76 mL 28.79 mL 57.57 mL
1 mM 2.88 mL 14.39 mL 28.79 mL
5 mM 0.58 mL 2.88 mL 5.76 mL
Useful Calculator

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