H-151 is a highly potent, selective and covalent antagonist of STING, reduces TBK1 phosphorylation and suppresses human STING palmitoylation.
Product Information
Catalog Num
A19676
Formula
C17H17N3O
Molecular Weight
279.34
CAS Number
941987-60-6
SMILES
O=C(NC1=CNC2=C1C=CC=C2)NC3=CC=C(CC)C=C3
Synonyms
H 151; H151
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
Solubility
In vitro
DMSO
52 mg/mL (186.15 mM)
Water
Insoluble
Ethanol
13 mg/mL (46.53 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
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