HBV-IN-25 is a potent HBV cccDNA reducer with demonstrated oral bioavailability. It exhibits anti-HBeAg potency and anti-HBV activity, with IC50 values of 0.58 μM and 1.15 μM, respectively. HBV-IN-25 possesses excellent aqueous solubility (LYSA > 452 μg/mL) and favorable pharmacokinetic properties, with no observed cellular toxicity. This compound is suited for research applications focused on hepatitis B virus infection and its associated pathologies.
HBV-IN-25 is a potent HBV cccDNA reducer with demonstrated oral bioavailability. It exhibits anti-HBeAg potency and anti-HBV activity, with IC50 values of 0.58 μM and 1.15 μM, respectively. HBV-IN-25 possesses excellent aqueous solubility (LYSA > 452 μg/mL) and favorable pharmacokinetic properties, with no observed cellular toxicity. This compound is suited for research applications focused on hepatitis B virus infection and its associated pathologies.
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