HC-030031

Catalog No.: A13278

TRPA1 inhibitor

HC-030031

HC-030031 Chemical Structure

CAS NO. 349085-38-7

HC-030031 is a selective TRPA1 blocker, antagonizing TRPA1-mediated calcium influx induced by AITC and formalin (IC50 = 6.2 and 5.3 uM, respectively).

Availability: In stock

Package Price Qty
50 mg
$120.00
100 mg
$180.00
200 mg
$250.00
10mM * 1mL in DMSO
$55.00
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Biological Activity

HC-030031 is a selective TRPA1 blocker, antagonizing TRPA1-mediated calcium influx induced by AITC and formalin (IC50 = 6.2 and 5.3 uM, respectively).
Targets
TRPA1
In vitro (25°C) DMSO 32 mg/mL (90.04 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% methylcellulose 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.14 mL 140.69 mL 281.37 mL
0.5 mM 5.63 mL 28.14 mL 56.27 mL
1 mM 2.81 mL 14.07 mL 28.14 mL
5 mM 0.56 mL 2.81 mL 5.63 mL

*The above data is based on the productmolecular weight 355.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13278
Actions Inhibitor
M. Wt 355.4
Formula C18H21N5O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 349085-38-7
Synonyms HC030031
SMILES CC(C)C1=CC=C(C=C1)NC(=O)CN2C=NC3=C2C(=O)N(C(=O)N3C)C

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