HEC96719 is a selective tricyclic agonist of the farnesoid X receptor (FXR) that demonstrates potent activity with EC50 values of 1.37 nM and 1.55 nM in time-resolved fluorescence energy transfer (TR-FRET) and luciferase reporter assays, respectively. This compound has shown significant efficacy in improving non-alcoholic steatohepatitis (NASH) and liver fibrosis, exhibiting favorable distribution in liver and intestinal tissues. HEC96719 is valuable for research focusing on non-alcoholic steatohepatitis and related liver conditions.
HEC96719 is a selective tricyclic agonist of the farnesoid X receptor (FXR) that demonstrates potent activity with EC50 values of 1.37 nM and 1.55 nM in time-resolved fluorescence energy transfer (TR-FRET) and luciferase reporter assays, respectively. This compound has shown significant efficacy in improving non-alcoholic steatohepatitis (NASH) and liver fibrosis, exhibiting favorable distribution in liver and intestinal tissues. HEC96719 is valuable for research focusing on non-alcoholic steatohepatitis and related liver conditions.
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