Hh-Ag1.5

Catalog No.: A12920

Hedgehog inhibitor

Hh-Ag1.5

Hh-Ag1.5 Chemical Structure

CAS NO. 612542-14-0

Hh-Ag1.5 is one of the most potent and selective small-molecule agonists of the Hedgehog pathway, targeting Smoothened (Smo) with an EC50 ~1 nM.

Availability: In stock

Package Price Qty
2 mg
$180.00
5 mg
$350.00
10 mg
$600.00
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Biological Activity

Hh-Ag1.5 is one of the most potent and selective small-molecule agonists of the Hedgehog pathway, targeting Smoothened (Smo) with an EC50 ~1 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.01 mL 95.05 mL 190.1 mL
0.5 mM 3.8 mL 19.01 mL 38.02 mL
1 mM 1.9 mL 9.5 mL 19.01 mL
5 mM 0.38 mL 1.9 mL 3.8 mL

*The above data is based on the productmolecular weight 526.04. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12920
Actions Inhibitor
CAS No. 612542-14-0
Formula C28H26ClF2N3OS ?
M. Wt 526.04
Purity >98%
SMILES O=C(C1=C(Cl)C2=C(F)C=CC(F)=C2S1)N([[email protected]]3CC[[email protected]](NC)CC3)CC4=CC=CC(C5=CC=NC=C5)=C4
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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