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Biological Activity
Hh-Ag1.5 is one of the most potent and selective small-molecule agonists of the Hedgehog pathway, targeting Smoothened (Smo) with an EC50 ~1 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.01 mL | 95.05 mL | 190.1 mL |
| 0.5 mM | 3.8 mL | 19.01 mL | 38.02 mL |
| 1 mM | 1.9 mL | 9.5 mL | 19.01 mL |
| 5 mM | 0.38 mL | 1.9 mL | 3.8 mL |
*The above data is based on the productmolecular weight 526.04. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12920 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 612542-14-0 |
| Formula | C28H26ClF2N3OS |
| M. Wt | 526.04 |
| Purity | >98% |
| SMILES | O=C(C1=C(Cl)C2=C(F)C=CC(F)=C2S1)N([[email protected]]3CC[[email protected]](NC)CC3)CC4=CC=CC(C5=CC=NC=C5)=C4 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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