17 Items

per page
Set Descending Direction
Catalog No.
Product Name
Product Information
Product Citation
  1. Hedgehog signaling inhibitor

    Cyclopamine is a Smo or hedgehog signaling pathway inhibitor.
  2. Hedgehog antagonist

    GDC-0449 (Vismodegib) is a more potent novel and specific synthetic oral hedgehog pathway inhibitor with an IC50 of 3 nM.
  3. SMO Antagonist

    LY2940680 has been shown to affect a cancer cell signaling pathway initiated by the Hedgehog (Hh) protein.
  4. Hedgehog inhibitor

    TAK-441 is a pyrrolo[3,2-c]pyridine derivative, as a highly potent and orally active hedgehog signaling inhibitor.
  5. GLI antagonist

    GANT 58 is a potent Gli antagonist that inhibits GLI1-induced transcription with IC50 of 5 μM.
  6. Hedgehog signaling activator

    Purmorphamine is a 2,6,9-trisubstituted purine that promotes the differentiation of both human and mouse mesenchymal progenitor cells into osteoblasts.
  7. HhAntag is a small molecule inhibitor of GLI1-mediated transcription, an essential down-stream element of the Hedgehog (Hh) pathway.
  8. Hedgehog inhibitor

    Hh-Ag1.5 is one of the most potent and selective small-molecule agonists of the Hedgehog pathway, targeting Smoothened (Smo) with an EC50 ~1 nM.
  9. Hedgehog inhibitor

    JK184 is potent downstream hedgehog (Hh) signaling inhibitor that prevents Gli-dependent transcriptional activity (IC50 = 30 nM).
  10. Sonic hedgehog inhibitor

    SANT-1 is a potent, cell-permeable inhibitor of Sonic hedgehog (Shh) signaling; high affinity antagonist of smoothened activity (KD = 1.2 nM). Inhibits smoothened agonist effects with an IC50 of 20 nM (in Shh-LIGHT2 cells).
  11. GLI antagonist

    GANT61 is an inhibitor for GLI1 as well as GLI2-induced transcription, inhibits hedgehog with IC50 of 5 μM, displays selectivity over other pathways, such as TNF and glucocorticoid receptor gene transactivation.
  12. Hedgehog inhibitor

    MK-4101 is a potent and selective inhibitor of the Hedgehog Pathway.
  13. Hhat inhibitor

    RU-SKI 43 is a small molecule inhibitor of Hhat(Hedgehog acyltransferase), the enzyme responsible for the attachment of palmitate onto Shh.
  14. hedgehog inhibitor

    HPI-4 is a hedgehog (Hh) signaling pathway inhibitor with median inhibitory concentration (IC50) less than 10 μM.
  15. Hedgehog inhibitor

    Mebendazole is a highly effective, broad-spectrum antihelmintic indicated for the treatment of nematode infestations; has been found as a hedgehog inhibitor.
  16. dyneins 1/2 inhibitor

    Dynarrestin is a aminothiazole inhibitor of cytoplasmic dyneins 1 and 2.
  17. cholesterol synthesis/Hedgehog inhibitor

    U18666A, a cell permeable drug, is a cholesterol synthesis and transport inhibitor.

17 Items

per page
Set Descending Direction