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Publications citing Adooq Products
Chemical Information
| Catalog Num | A16042 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 369.4 |
| Formula | C20H11N5OS |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 487020-03-1 |
| Synonyms | HI-TOPK-032, HI-TOPK032, HI-TOPK 032 |
| SMILES | O=C(C1=CC=CS1)NC2=CC3=C(C#N)C4=NC5=CC=CC=C5N=C4N3C=C2 |
Description |
HI-TOPK-032 is a potent and selective TOPK inhibitor. In vitro, HI-TOPK-032 strongly suppressed TOPK kinase activity but had little effect on extracellular signal?Cregulated kinase 1 (ERK1), c-jun??NH2??kinase 1, or p38 kinase activities. | |||||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27.07 mL | 135.35 mL | 270.71mL |
| 0.5 mM | 5.41 mL | 27.07 mL | 54.14 mL |
| 1 mM | 2.71 mL | 13.54 mL | 27.07 mL |
| 5 mM | 0.54 mL | 2.71 mL | 5.41 mL |
*The above data is based on the productmolecular weight 369.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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