HI TOPK 032

Catalog No.: A16042

TOPK inhibitor

HI TOPK 032

HI TOPK 032 Chemical Structure

CAS NO. 487020-03-1

HI-TOPK-032 is a potent and selective TOPK inhibitor. In vitro, HI-TOPK-032 strongly suppressed TOPK kinase activity but had little effect on extracellular signal-regulated kinase 1 (ERK1), c-jun-NH2-kinase 1, or p38 kinase activities.

Availability: In stock

Package Price Qty
5 mg
$120.00
10 mg
$200.00
50 mg
$820.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

HI-TOPK-032 is a potent and selective TOPK inhibitor. In vitro, HI-TOPK-032 strongly suppressed TOPK kinase activity but had little effect on extracellular signal-regulated kinase 1 (ERK1), c-jun-NH2-kinase 1, or p38 kinase activities.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.07 mL 135.35 mL 270.71 mL
0.5 mM 5.41 mL 27.07 mL 54.14 mL
1 mM 2.71 mL 13.54 mL 27.07 mL
5 mM 0.54 mL 2.71 mL 5.41 mL

*The above data is based on the productmolecular weight 369.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16042
Actions Inhibitor
M. Wt 369.4
Formula C20H11N5OS
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 487020-03-1
Synonyms HI-TOPK-032, HI-TOPK032, HI-TOPK 032
SMILES O=C(C1=CC=CS1)NC2=CC3=C(C#N)C4=NC5=CC=CC=C5N=C4N3C=C2

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