HIV-1 Inhibitor-28 targets the HIV-1 reverse transcriptase (RT) to effectively inhibit viral replication. This compound demonstrates high potency with an EC50 of 58 nM against wild-type HIV-1 and an IC50 of 3.37 μM for HIV-1 RT, while exhibiting low cytotoxicity in MT-4 cells (CC50 = 38.6 μM). HIV-1 Inhibitor-28 is suitable for research applications focused on AIDS and the development of antiviral therapies.
HIV-1 Inhibitor-28 targets the HIV-1 reverse transcriptase (RT) to effectively inhibit viral replication. This compound demonstrates high potency with an EC50 of 58 nM against wild-type HIV-1 and an IC50 of 3.37 μM for HIV-1 RT, while exhibiting low cytotoxicity in MT-4 cells (CC50 = 38.6 μM). HIV-1 Inhibitor-28 is suitable for research applications focused on AIDS and the development of antiviral therapies.
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