HO-PEG21-OH is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound facilitates selective degradation of target proteins by linking an E3 ligase to the protein of interest, promoting ubiquitination and subsequent proteasomal degradation. HO-PEG21-OH is integral for advancing research in targeted protein degradation and understanding protein regulation mechanisms in various biological contexts.
HO-PEG21-OH is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound facilitates selective degradation of target proteins by linking an E3 ligase to the protein of interest, promoting ubiquitination and subsequent proteasomal degradation. HO-PEG21-OH is integral for advancing research in targeted protein degradation and understanding protein regulation mechanisms in various biological contexts.
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