HO-PEG6-CH2COOH is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the conjugation of different protein-targeting moieties, enabling the selective degradation of target proteins through the ubiquitin-proteasome pathway. Its incorporation into PROTACs allows for enhanced solubility and improved cellular uptake, making it a valuable tool in targeted protein degradation research.
HO-PEG6-CH2COOH is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the conjugation of different protein-targeting moieties, enabling the selective degradation of target proteins through the ubiquitin-proteasome pathway. Its incorporation into PROTACs allows for enhanced solubility and improved cellular uptake, making it a valuable tool in targeted protein degradation research.
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