HPK1-IN-14

Catalog No.: A65755
HPK1 Inhibitor
HPK1-IN-14 is a selective inhibitor of HPK1, a serine/threonine protein kinase that is part of the MAP4K family and is found in hematopoietic progenitor cells. This compound exhibits significant potential for inhibiting HPK1 activity, making it a valuable tool for research into HPK1-related diseases and cellular signaling pathways. Researchers can utilize HPK1-IN-14 to investigate the roles of HPK1 in various biological processes and therapeutic contexts.
Grouped product items
Size Price Stock Qty
25mg
$1,800.00
In stock
50mg
$2,285.00
In stock
100mg
$2,815.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionHPK1-IN-14 is a selective inhibitor of HPK1, a serine/threonine protein kinase that is part of the MAP4K family and is found in hematopoietic progenitor cells. This compound exhibits significant potential for inhibiting HPK1 activity, making it a valuable tool for research into HPK1-related diseases and cellular signaling pathways. Researchers can utilize HPK1-IN-14 to investigate the roles of HPK1 in various biological processes and therapeutic contexts.
Product Information
Catalog NumA65755
FormulaC24H23FN6O2
Molecular Weight446.48
CAS Number2734168-45-5
SMILESFC1=C(C2=NC3=C(NN=C3C4=CC(OCC5N6CCN(C5)C)=C6C=C4)C=N2)C(OC)=CC=C1
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