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Product Name
Product Information
Product Citation
  1. MAP4K4 inhibitor

    GNE-495 is a potent and selective MAP4K4 inhibitor with an IC50 of 3.7 nM.
  2. TAK1/MAP4K2 inhibitor

    NG25, a TAK1 inhibitor, inhibited the activation of IKK by TLR7 and TLR9 agonists and prevented the secretion of type 1 IFNs induced by these ligands in Gen2.2 cells.
  3. MAP4K4 inhibitor

    PF-06260933 is a potent, selective, orally available MAP4K4 inhibitor with IC50 of 3.7 nM.
  4. MAP4K4 inhibitor

    DMX-5804 is a potent, orally active and selective MAP4K4 inhibitor, with an IC50 of 3 nM, a pIC50 of 8.55 for human MAP4K4, less potent on MINK1/MAP4K6 (pIC50, 8.18), and TNIK/MAP4K7 (pIC50, 7.96).

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