HPP-9

Name: HPP-9
Brand: Adooq Bioscience
SKU: A44276
Rating: 5 (288 reviews)

Catalog No.: A44276

Hedgehog Pathway Inhibitor

HPP-9 is a Hedgehog Pathway inhibitor designed as a Proteolysis-Targeting Chimera (PROTAC) that effectively degrades BET bromodomains. With a pIC50 of 6.71, HPP-9 exhibits significant antitumor activity. This compound is valuable for research applications focused on cancer biology and the modulation of the Hedgehog signaling pathway.

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HPP-9 3093738-79-2 Hedgehog Pathway Inhibitor

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Biological Activity

Description	HPP-9 is a Hedgehog Pathway inhibitor designed as a Proteolysis-Targeting Chimera (PROTAC) that effectively degrades BET bromodomains. With a pIC50 of 6.71, HPP-9 exhibits significant antitumor activity. This compound is valuable for research applications focused on cancer biology and the modulation of the Hedgehog signaling pathway.

Product Information

Catalog Num	A44276
Formula	C49H52N6O11
Molecular Weight	900.97
CAS Number	3093738-79-2
SMILES	CC1=C(C(OCCOC)=O)C(C2=CC(OCC3=CN(CCCCCCOC4=CC=CC(C(N5C6CCC(NC6=O)=O)=O)=C4C5=O)N=N3)=CC=C2)C7=C(N1)CC(C8=C(OC)C=CC=C8)CC7=O

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