HS-PEG5-CH2CH2N3 serves as a PEG-based PROTAC linker and primarily targets the synthesis of PROTACs. This compound is a versatile click chemistry reagent featuring an azide functional group that participates in copper-catalyzed azide-alkyne cycloaddition reactions with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition reactions with molecules containing DBCO or BCN groups, facilitating efficient conjugation and molecular assembly in chemical biology applications.
HS-PEG5-CH2CH2N3 serves as a PEG-based PROTAC linker and primarily targets the synthesis of PROTACs. This compound is a versatile click chemistry reagent featuring an azide functional group that participates in copper-catalyzed azide-alkyne cycloaddition reactions with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition reactions with molecules containing DBCO or BCN groups, facilitating efficient conjugation and molecular assembly in chemical biology applications.
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