HS-PEG7-CH2CH2N3 is a PEG-based linker targeting the development of PROTACs (Proteolysis Targeting Chimeras). It features an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing compounds. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN functionalities. This versatile linker is essential for researchers focusing on targeted protein degradation mechanisms in chemical biology.
HS-PEG7-CH2CH2N3 is a PEG-based linker targeting the development of PROTACs (Proteolysis Targeting Chimeras). It features an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing compounds. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN functionalities. This versatile linker is essential for researchers focusing on targeted protein degradation mechanisms in chemical biology.
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