HSD1590

Name: HSD1590
Brand: Adooq Bioscience
SKU: A24491
Rating: 5 (288 reviews)

Catalog No.: A24491

ROCK 1/2 inhibitor

HSD1590 is a potent inhibitor of Rho-associated protein kinases, with IC₅₀ values of 1.22 nM for ROCK1 and 0.51 nM for ROCK2. It exhibits strong binding affinity to ROCK isoforms (K\_d < 2 nM) and demonstrates low cytotoxicity, making it suitable for further research applications.

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Grouped product items
Size	Price	Stock
5mg	$360.00	In stock
10mg	$620.00	In stock
50mg	$1,840.00	In stock
100mg	$3,600.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	HSD1590 is a potent inhibitor of Rho-associated protein kinases, with IC₅₀ values of 1.22 nM for ROCK1 and 0.51 nM for ROCK2. It exhibits strong binding affinity to ROCK isoforms (K\_d < 2 nM) and demonstrates low cytotoxicity, making it suitable for further research applications.

Product Information

Catalog Num	A24491
Formula	C20H18BN3O3
Molecular Weight	359.19
CAS Number	2379279-96-4
SMILES	COC(C(B(O)O)=CC=C1)=C1C(C2=C3CCC2)=NC4=C3C(C=NN5)=C5C=C4
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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