HSP-990

Catalog No.: A12850

HSP90 Inhibitor

HSP-990

HSP-990 Chemical Structure

CAS NO. 934343-74-5

HSP990 is an orally bioavailable inhibitor of human heat-shock protein 90 (Hsp90) with potential antineoplastic activity.

Availability: In stock

Package Price Qty
5 mg
$70.00
10 mg
$120.00
25 mg
$240.00
50 mg
$400.00
10mM * 1mL in DMSO
$112.00
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Biological Activity

HSP990 is an orally bioavailable inhibitor of human heat-shock protein 90 (Hsp90) with potential antineoplastic activity.
Targets
HSP90α HSP90β
0.6 nM0.8 nM
In vitro DMSO 65 mg/mL (171.32 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.36 mL 131.79 mL 263.58 mL
0.5 mM 5.27 mL 26.36 mL 52.72 mL
1 mM 2.64 mL 13.18 mL 26.36 mL
5 mM 0.53 mL 2.64 mL 5.27 mL

*The above data is based on the productmolecular weight 379.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12850
Actions Inhibitor
CAS No. 934343-74-5
Formula C20H18FN5O2
M. Wt 379.39
Solubility DMSO
Purity >98%
Synonyms HSP990, HSP 990, NVP-HSP990
SMILES CC1=NC(=NC2=C1C(=O)N[[email protected]](C2)C3=C(C=C(C=C3)F)C4=NC(=CC=C4)OC)N
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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