HTH-01-015

Catalog No.: A16281

NUAK1 inhibitor

HTH-01-015

HTH-01-015 Chemical Structure

CAS NO. 1613724-42-7

HTH-01-015 is a potent and selective inhibitor of NUAK1 (IC50 = 100 nM) and does not affect the activity of a panel of 139 other kinases, including additional AMPK family members.

Availability: In stock

Package Price Qty
5 mg
$90.00
10 mg
$120.00
50 mg
$400.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

HTH-01-015 is a potent and selective inhibitor of NUAK1 (IC50 = 100 nM) and does not affect the activity of a panel of 139 other kinases, including additional AMPK family members.
Targets
NUAK1 NUAK2
100 nM>10 μM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.34 mL 106.71 mL 213.42 mL
0.5 mM 4.27 mL 21.34 mL 42.68 mL
1 mM 2.13 mL 10.67 mL 21.34 mL
5 mM 0.43 mL 2.13 mL 4.27 mL

*The above data is based on the productmolecular weight 468.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A16281
Actions Inhibitor
M. Wt 468.56
Formula C26H28N8O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1613724-42-7
Synonyms HTH01-015, HTH 01-015
SMILES CC1=C(N(C)C(C2=CC(C=CC=C3)=C3C=C2N4C)=O)C4=NC(NC5=CN(N=C5)C6CCNCC6)=N1

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