Hydroxy-PEG4-CH2COOH sodium salt

Catalog No.: A83363
PROTAC Linker
Hydroxy-PEG4-CH2COOH sodium salt is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTAC (proteolysis targeting chimera) molecules. Its hydroxyl group enhances solubility and protein interaction, facilitating the targeted degradation of specific proteins in cellular systems. This reagent is essential for researchers developing innovative PROTAC therapies in applications including cancer treatment and protein regulation studies.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionHydroxy-PEG4-CH2COOH sodium salt is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTAC (proteolysis targeting chimera) molecules. Its hydroxyl group enhances solubility and protein interaction, facilitating the targeted degradation of specific proteins in cellular systems. This reagent is essential for researchers developing innovative PROTAC therapies in applications including cancer treatment and protein regulation studies.
Product Information
Catalog NumA83363
FormulaC10H19NaO7
Molecular Weight274.24
CAS Number73349-20-9
SMILESO=C(COCCOCCOCCOCCO)O[Na]
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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    C2

    V2