I3MT-3

Catalog No.: A84785
3MST Inhibitor
I3MT-3 is a selective inhibitor of 3-Mercaptopyruvate sulfurtransferase (3MST), exhibiting an IC50 value of 2.7 μM, demonstrating its potency against this target. The compound selectively interacts with a persulfurated cysteine residue within the active site of 3MST, ensuring minimal off-target activity. I3MT-3 is ideal for studies investigating the role of hydrogen sulfide and its metabolic pathways, as well as potential therapeutic applications related to sulfur metabolism.
Grouped product items
Size Price Stock Qty
1mg
$55.00
In stock
5mg
$140.00
In stock
10mg
$230.00
In stock
25mg
$380.00
In stock
50mg
$530.00
In stock
100mg
$715.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionI3MT-3 is a selective inhibitor of 3-Mercaptopyruvate sulfurtransferase (3MST), exhibiting an IC50 value of 2.7 μM, demonstrating its potency against this target. The compound selectively interacts with a persulfurated cysteine residue within the active site of 3MST, ensuring minimal off-target activity. I3MT-3 is ideal for studies investigating the role of hydrogen sulfide and its metabolic pathways, as well as potential therapeutic applications related to sulfur metabolism.
Product Information
Catalog NumA84785
FormulaC17H14N2O2S
Molecular Weight310.37
CAS Number459420-09-8
SMILESO=C1NC(SCC(C2=C3C=CC=CC3=CC=C2)=O)=NC(C)=C1
SynonymsHMPSNE
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