Ibiglustat

Catalog No.: A21083

GCS inhibitor

Ibiglustat

Ibiglustat Chemical Structure

CAS NO. 1401090-53-6

Ibiglustat (Venglustat), a potential therapy for PD Parkinson??s disease, SRT in Fabry??s and Gaucher??s, is a selective, allosteric inhibitor of glucosylceramide synthase (GCS) with ability to cross the blood-brain barrier.

Availability: In stock

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2 mg

Regular Price: $90.00

Special Price $72.00

5 mg

Regular Price: $180.00

Special Price $144.00

10 mg

Regular Price: $350.00

Special Price $280.00

50 mg

Regular Price: $1,030.00

Special Price $824.00

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Biological Activity

Ibiglustat (Venglustat), a potential therapy for PD Parkinson??s disease, SRT in Fabry??s and Gaucher??s, is a selective, allosteric inhibitor of glucosylceramide synthase (GCS) with ability to cross the blood-brain barrier.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.67 mL 128.37 mL 256.75 mL
0.5 mM 5.13 mL 25.67 mL 51.35 mL
1 mM 2.57 mL 12.84 mL 25.67 mL
5 mM 0.51 mL 2.57 mL 5.13 mL

*The above data is based on the productmolecular weight 389.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21083
Actions Inhibitor
CAS No. 1401090-53-6
Formula C20H24FN3O2S
M. Wt 389.49
Purity >98%
Synonyms Venglustat; SAR402671, SAR 402671, SAR-402671; GZ402671, GZ 402671, GZ-402671
SMILES O=C(O[[email protected]@H]1CN2CCC1CC2)NC(C)(C3=CSC(C4=CC=C(F)C=C4)=N3)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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