Icariin

Catalog No.: A10464

PDE5 inhibitor

Icariin

Icariin Chemical Structure

CAS NO. 489-32-7

Icariin is inhibitory to all three PDE5 isoforms that inhibits PDE5A1, A2, and A3 with an IC50 value of 1.0, 0.75, and 1.1 microM, respectively.

Availability: In stock

Package Price Qty
50 mg

Regular Price: $60.00

Special Price $54.00

100 mg

Regular Price: $100.00

Special Price $90.00

250 mg

Regular Price: $200.00

Special Price $180.00

500 mg

Regular Price: $320.00

Special Price $288.00

10mM * 1mL in DMSO

Regular Price: $67.00

Special Price $60.30

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Icariin is inhibitory to all three PDE5 isoforms that inhibits PDE5A1, A2, and A3 with an IC50 value of 1.0, 0.75, and 1.1 microM, respectively.
Targets
PDE5
0.432 μM
In vitro DMSO 50 mg/mL (73.89 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 14.78 mL 73.89 mL 147.78 mL
0.5 mM 2.96 mL 14.78 mL 29.56 mL
1 mM 1.48 mL 7.39 mL 14.78 mL
5 mM 0.3 mL 1.48 mL 2.96 mL

*The above data is based on the productmolecular weight 676.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A10464
Actions Inhibitor
M. Wt 676.7
Formula C33H40O15
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 489-32-7
Synonyms N/A
SMILES C[[email protected]]1[[email protected]@H]([[email protected]]([[email protected]]([[email protected]@H](O1)OC2=C(OC3=C(C2=O)C(=CC(=C3CC=C(C)C)O[[email protected]]4[[email protected]@H]([[email protected]]([[email protected]@H]([[email protected]](O4)CO)O)O)O)O)C5=CC=C(C=C5)OC)O)O)O

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