Icatibant

Catalog No.: A18074

Bradykinin B2 receptors antagonist

Icatibant

Icatibant Chemical Structure

CAS NO. 130308-48-4

Icatibant (HOE-140) is a selective and specific antagonist of bradykinin B2 receptor with IC50 and Ki of 1.07 nM and 0.798 nM respectively.

Availability: In stock

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1 mg

Regular Price: $250.00

Special Price $200.00

5 mg

Regular Price: $500.00

Special Price $400.00

10 mg

Regular Price: $700.00

Special Price $560.00

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Biological Activity

Icatibant (HOE-140) is a selective and specific antagonist of bradykinin B2 receptor with IC50 and Ki of 1.07 nM and 0.798 nM respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 7.67 mL 38.33 mL 76.66 mL
0.5 mM 1.53 mL 7.67 mL 15.33 mL
1 mM 0.77 mL 3.83 mL 7.67 mL
5 mM 0.15 mL 0.77 mL 1.53 mL

*The above data is based on the productmolecular weight 1304.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18074
Actions Antagonist
CAS No. 130308-48-4
Formula C59H89N19O13S
M. Wt 1304.52
Purity >98%
Synonyms Firazyr
SMILES N=C(N)NC(C(C1NCC2=C(C=CC=C2)C1)=O)CC[[email protected]@H](C(O)=O)N(C([[email protected]](CO)N(C(CN(C([[email protected]]3N(C([[email protected]](CCCNC(N)=N)NC([[email protected]@H](CCCNC(N)=N)N)=O)=O)CCC3)=O)C(C4NC[[email protected]](O)C4)=O)=O)C([[email protected]](CC5=CC=CS5)N)=O)=O)C(C6N[[email protected]@]7([H])CCCC[[email protected]@]7([H])C6)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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