Trusted by 10,000+ Scientists since 2006



Wnt/beta-catenin inhibitor

0 Customer Reviews
Catalog No. A11039

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
ICG-001 5mg A11039-5

Regular Price: $60.00

Special Price: $54.00

ICG-001 10mg A11039-10

Regular Price: $100.00

Special Price: $90.00

ICG-001 25mg A11039-25

Regular Price: $240.00

Special Price: $216.00

ICG-001 100mg A11039-100

Regular Price: $550.00

Special Price: $495.00

ICG-001 10mM * 1mL in DMSO A11039-10mM-D

Regular Price: $125.00

Special Price: $112.50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

ICG-001 is a specific inhibitor of Wnt/β-catenin signaling pathway that inhibits β-catenin/cyclic AMP response element-binding (CREB) protein transcription (IC50=3 microM) .


Double click on above image to view full picture

Zoom Out
Zoom In

More Views

Publications citing Adooq Products
ICG-001  Citations (3)
  • Kim JH, .et al. Small Heterodimer Partner Controls the Virus-Mediated Antiviral Immune Response by Targeting CREB-Binding Protein in the Nucleus, Cell Rep, 2019, May 14;27(7):2105-2118.e5 PMID: 31091449
  • Yamaoka R, .et al. CD90 expression in human intrahepatic cholangiocarcinoma is associated with lymph node metastasis and poor prognosis, J Surg Oncol, 2018, Sep;118(4):664-674 PMID: 30196535
  • Aida Y, .et al. Wnt3a promotes differentiation of human bone marrow-derived mesenchymal stem cells into cementoblast-like cells, In Vitro Cell Dev Biol Anim, 2018, Jun;54(6):468-476 PMID: 29785536

Chemical Information

Catalog Num A11039
Actions Inhibitor
M. Wt 548.6
Formula C33H32N4O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 780757-88-2
Synonyms ICG001
SMILES C1CN([[email protected]]2CN(C(=O)[[email protected]@H](N2C1=O)CC3=CC=C(C=C3)O)CC4=CC=CC5=CC=CC=C54)C(=O)NCC6=CC=CC=C6

Biological Activity

ICG-001 is a specific inhibitor of Wnt/β-catenin signaling pathway that inhibits β-catenin/cyclic AMP response element-binding (CREB) protein transcription (IC50=3 microM) .
CBP (Cell-free assay)
3 μM


Solubility (25°C)* In vitro DMSO 100 mg/mL (182.27 mM)
Water <1 mg/mL (<1 mM)
Ethanol 35 mg/mL (63.79 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.23 mL 91.14 mL 182.28mL
0.5 mM 3.65 mL 18.23 mL 36.46 mL
1 mM 1.82 mL 9.11 mL 18.23 mL
5 mM 0.36 mL 1.82 mL 3.65 mL

*The above data is based on the productmolecular weight 548.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

View Related Products By Research Topics

Ordering online

To place an order online, simply browse to the product you are interested in and click on the 'Add to Cart' button. To complete this process, you will need to confirm the size and quantity of the products that you require.

To complete an order you will need to register using our simple online registration process. We do not share your contact details with any third parties.

When you are ready to check out simply enter your PO number to complete the ordering process. Please ensure that you send us a copy of your PO by fax or email afterwards.  We will then liaise with you or your purchasing department to confirm the order.

Found your products but not ready to order?

Why not use our WishList feature to store lists of products? This convenient feature allows you to manage lists, append notes to products and share lists with co-workers or colleagues.

Ordering offline

You can email or fax us your purchase order and we will place the order for you. You can also phone us to place the order.  Our contact details are:

We require the following information to process your order:
  • The catalog number for each product. 
  • Your email address or fax number. 
  • Your name and telephone number. 
  • Shipping address and billing address.
  • Purchase order numbers.

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Similar product(s)

Keywords:buy ICG-001 | ICG-001 Supplier | purchase ICG-001 | ICG-001 cost | ICG-001 manufacturer | order ICG-001 | ICG-001 distributor | buy 780757-88-2| 780757-88-2 Supplier | purchase 780757-88-2 | 780757-88-2 cost | 780757-88-2 manufacturer | order 780757-88-2 | 780757-88-2 distributor