ICG-001

Catalog No.: A11039

Wnt/beta-catenin inhibitor

ICG-001 Chemical Structure

CAS NO. 780757-88-2

ICG-001 is a specific inhibitor of Wnt/β-catenin signaling pathway that inhibits β-catenin/cyclic AMP response element-binding (CREB) protein transcription (IC50=3 microM) .

Availability: In stock

Package Price Qty
5 mg
$60.00
10 mg
$100.00
25 mg
$240.00
100 mg
$550.00
10mM * 1mL in DMSO
$125.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

ICG-001 is a specific inhibitor of Wnt/β-catenin signaling pathway that inhibits β-catenin/cyclic AMP response element-binding (CREB) protein transcription (IC50=3 microM) .
Targets
CBP (Cell-free assay)
3 μM
In vitro DMSO 100 mg/mL (182.27 mM)
Water <1 mg/mL (<1 mM)
Ethanol 35 mg/mL (63.79 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.23 mL 91.14 mL 182.28 mL
0.5 mM 3.65 mL 18.23 mL 36.46 mL
1 mM 1.82 mL 9.11 mL 18.23 mL
5 mM 0.36 mL 1.82 mL 3.65 mL

*The above data is based on the productmolecular weight 548.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11039
Actions Inhibitor
M. Wt 548.6
Formula C33H32N4O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 780757-88-2
Synonyms ICG001
SMILES C1CN([[email protected]]2CN(C(=O)[[email protected]@H](N2C1=O)CC3=CC=C(C=C3)O)CC4=CC=CC5=CC=CC=C54)C(=O)NCC6=CC=CC=C6

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