IDO1-IN-16

Catalog No.: A75769
IDO1 Inhibitor
IDO1-IN-16 is a potent inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), demonstrating an IC50 of 127 nM against the holoenzyme. This compound is essential for research applications in immunology, particularly in studying tumor microenvironments and modulating immune responses. IDO1-IN-16 can aid in the development of novel therapeutic strategies for cancer and autoimmune diseases by inhibiting the enzymatic activity that leads to immune tolerance.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionIDO1-IN-16 is a potent inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), demonstrating an IC50 of 127 nM against the holoenzyme. This compound is essential for research applications in immunology, particularly in studying tumor microenvironments and modulating immune responses. IDO1-IN-16 can aid in the development of novel therapeutic strategies for cancer and autoimmune diseases by inhibiting the enzymatic activity that leads to immune tolerance.
Product Information
Catalog NumA75769
FormulaC25H35BrFN5O2
Molecular Weight536.48
CAS Number2677054-63-4
SMILESO=C(NCCC)NC1=CC(/C(NO)=N\C2=CC=C(C(Br)=C2)F)=CC=C1N(CC(C)C)CC(C)C
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