Signaling Pathway
Product type
Important Notice: For research use only. We do not sell to patients.
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| Discription | IM-12 is a cell-permeable indolylmaleimide that acts as a Glycogen synthase kinase 3β (GSK-3β) inhibitor, activating downstream components of canonical Wnt signaling. | ||
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| Catalog Num | A14196 |
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| Formula | C22H20FN3O2 |
| Molecular Weight | 377.41 |
| CAS Number | 1129669-05-1 |
| SMILES | CC1=C(C2=CC=CC=C2N1)C3=C(C(=O)N(C3=O)C)NCCC4=CC=C(C=C4)F |
| Synonyms | IM12, IM 12 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 72 mg/mL (190.77 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 10 mg/mL (26.49 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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| 0.1 mM | 26.5 mL | 132.48 mL | 264.96 mL |
| 0.5 mM | 5.3 mL | 26.5 mL | 52.99 mL |
| 1 mM | 2.65 mL | 13.25 mL | 26.5 mL |
| 5 mM | 0.53 mL | 2.65 mL | 5.3 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
