Total item
Cart Subtotal
$0.00 Biological Activity
IM-12 is a cell-permeable indolylmaleimide that acts as a Glycogen synthase kinase 3β (GSK-3β) inhibitor, activating downstream components of canonical Wnt signaling.
Targets
| GSK-3β | ||||
| 53 nM |
| In vitro | DMSO | 75 mg/mL (198.72 mM) | |
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | 10 mg/mL heating (26.49 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.5 mL | 132.48 mL | 264.96 mL |
| 0.5 mM | 5.3 mL | 26.5 mL | 52.99 mL |
| 1 mM | 2.65 mL | 13.25 mL | 26.5 mL |
| 5 mM | 0.53 mL | 2.65 mL | 5.3 mL |
*The above data is based on the productmolecular weight 377.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A14196 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 377.41 |
| Formula | C22H20FN3O2 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1129669-05-1 |
| Synonyms | IM12, IM 12 |
| SMILES | CC1=C(C2=CC=CC=C2N1)C3=C(C(=O)N(C3=O)C)NCCC4=CC=C(C=C4)F |
Product Tags
Product Questions
Product Questions
No Questions
Keywords:buy IM-12 | IM-12 Supplier | purchase IM-12 | IM-12 cost | IM-12 manufacturer | order IM-12 | IM-12 distributor | buy 1129669-05-1| 1129669-05-1 Supplier | purchase 1129669-05-1 | 1129669-05-1 cost | 1129669-05-1 manufacturer | order 1129669-05-1 | 1129669-05-1 distributor
Adooq Quality Guarantee
We promise all products perform as described.