IM-12

Catalog No.: A14196

GSK-3β inhibitor

IM-12

IM-12 Chemical Structure

CAS NO. 1129669-05-1

IM-12 is a cell-permeable indolylmaleimide that acts as a Glycogen synthase kinase 3β (GSK-3β) inhibitor, activating downstream components of canonical Wnt signaling.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $60.00

Special Price $48.00

25 mg

Regular Price: $120.00

Special Price $96.00

50 mg

Regular Price: $200.00

Special Price $160.00

100 mg

Regular Price: $350.00

Special Price $280.00

10mM * 1mL in DMSO
$82.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

IM-12 is a cell-permeable indolylmaleimide that acts as a Glycogen synthase kinase 3β (GSK-3β) inhibitor, activating downstream components of canonical Wnt signaling.
Targets
GSK-3β
53 nM
In vitro DMSO 75 mg/mL (198.72 mM)
Water <1 mg/mL (<1 mM)
Ethanol 10 mg/mL heating (26.49 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.5 mL 132.48 mL 264.96 mL
0.5 mM 5.3 mL 26.5 mL 52.99 mL
1 mM 2.65 mL 13.25 mL 26.5 mL
5 mM 0.53 mL 2.65 mL 5.3 mL

*The above data is based on the productmolecular weight 377.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A14196
Actions Inhibitor
M. Wt 377.41
Formula C22H20FN3O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1129669-05-1
Synonyms IM12, IM 12
SMILES CC1=C(C2=CC=CC=C2N1)C3=C(C(=O)N(C3=O)C)NCCC4=CC=C(C=C4)F

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