INCB39110 (Itacitinib)

Catalog No.: A14390

JAK1 Inhibitor

INCB39110 (Itacitinib)

INCB39110 (Itacitinib) Chemical Structure

CAS NO. 1334298-90-6

INCB39110 is a potent JAK1 tyrosine kinase inhibitor, which is currently in Phase II trials for the treatment of rheumatoid arthritis, myelofibrosis, rheumatoid arthritis and plaque psoriasis.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $350.00

Special Price $280.00

10 mg

Regular Price: $500.00

Special Price $400.00

25 mg

Regular Price: $1,000.00

Special Price $800.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

INCB39110 is a potent JAK1 tyrosine kinase inhibitor, which is currently in Phase II trials for the treatment of rheumatoid arthritis, myelofibrosis, rheumatoid arthritis and plaque psoriasis.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.07 mL 90.33 mL 180.67 mL
0.5 mM 3.61 mL 18.07 mL 36.13 mL
1 mM 1.81 mL 9.03 mL 18.07 mL
5 mM 0.36 mL 1.81 mL 3.61 mL

*The above data is based on the productmolecular weight 553.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A14390
Actions Inhibitor
M. Wt 553.51
Formula C26H23F4N9O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1334298-90-6
Synonyms INCB 39110, INCB-39110, INCB039110, INCB-039110, INCB 039110
SMILES N#CCC1(N2N=CC(C3=C4C(NC=C4)=NC=N3)=C2)CN(C5CCN(C(C6=C(F)C(C(F)(F)F)=NC=C6)=O)CC5)C1

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