Signaling Pathway
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| Discription | INCB39110 is a potent JAK1 tyrosine kinase inhibitor, which is currently in Phase II trials for the treatment of rheumatoid arthritis, myelofibrosis, rheumatoid arthritis and plaque psoriasis. | ||
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| Catalog Num | A14390 |
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| Formula | C26H23F4N9O |
| Molecular Weight | 553.51 |
| CAS Number | 1334298-90-6 |
| SMILES | N#CCC1(N2N=CC(C3=C4C(NC=C4)=NC=N3)=C2)CN(C5CCN(C(C6=C(F)C(C(F)(F)F)=NC=C6)=O)CC5)C1 |
| Synonyms | INCB 39110, INCB-39110, INCB039110, INCB-039110, INCB 039110 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 88 mg/mL (158.98 mM) | |
| Water | Insoluble | ||
| Ethanol | 88 mg/mL (158.98 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.07 mL | 90.33 mL | 180.67 mL |
| 0.5 mM | 3.61 mL | 18.07 mL | 36.13 mL |
| 1 mM | 1.81 mL | 9.03 mL | 18.07 mL |
| 5 mM | 0.36 mL | 1.81 mL | 3.61 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
