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Biological Activity
INCB8761(PF-4136309) is a potent, selective, and orally bioavailable CCR2 antagonist.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.59 mL | 87.94 mL | 175.87 mL |
| 0.5 mM | 3.52 mL | 17.59 mL | 35.17 mL |
| 1 mM | 1.76 mL | 8.79 mL | 17.59 mL |
| 5 mM | 0.35 mL | 1.76 mL | 3.52 mL |
*The above data is based on the productmolecular weight 568.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11136 |
|---|---|
| Actions | Antagonist |
| CAS No. | 857679-55-1, 1341224-83-6 |
| Formula | C29H31F3N6O3 |
| M. Wt | 568.6 |
| Purity | >98% |
| Synonyms | INCB-8761,PF4136309 |
| SMILES | C1CN(C[[email protected]]1NC2CCC(CC2)(C3=NC=C(C=C3)C4=NC=CC=N4)O)C(=O)CNC(=O)C5=CC(=CC=C5)C(F)(F)F |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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